I’ve come across some projects I really dig. Though I’d share:
ChemHacker is building an open source scanning tunneling microscope: http://www.chemhacker.com/topics/stm/
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Ivan Bozovic has fabricated a nanometer scale superconductor at Brookhaven National Laboratory:
http://www.sciencedaily.com/releases/2010/06/100614092602.htm
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Junior has hacked together an incredible SLA style DIY 3D printer:
http://3dhomemade.blogspot.com/
This project has sparked my interest in the amazing Digital Light Processing technology.
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Kenneth V. Noren shows genetic algorithms can design electronic circuits!
http://www.mrc.uidaho.edu/mrc/people/knoren/GAs/B-159_paper.PDF
Prometheus Fusion Perfection 
myself i’m working on a combinatoral digital logic evolver. it takes two 32-bit inputs and produces 1 32-bit ouput. i have cpu code running smoothly. now i’m in the process of translating over to gpu code, and adding lamarkian evolution to the output layer.
We chatted in NY!
http://www.dnautics.com/jason/
My machine’s a lot simpler, and I’m almost done. Keep up the good work. Your stuff is very inspiring.